When you finish working on your experiment, you can sign it by clicking on the "Sign" button at the upper part of your Experiment page.
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This permission is extended to all experiment editors, not just the experiment's assignee.
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A window will open with the option to add a comment to other users.

Click "Sign" to continue.
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Then, you will need to enter your username and password to confirm the signature. Click "Confirm" to sign.
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A timestamp will be added under the experiment name when the experiment is signed.

Signed experiments cannot be edited in any way, although comments can still be written in the discussion thread. The signature can be reverted, making the experiment editable again if changes are required.
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To revert the signature, click "Revert signature" at the upper part of the experiment page.
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In the opened window with your email and password, click "Confirm" to revert the signature.
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If single sign-on is enabled for your account, all signatures will be done by clicking on the confirm button without the login credentials.

* When a signature flow is applied to a project, only members who were defined in that flow will have the option to witness all project-related experiments (even if their role does not include the 'Can witness' privilege).